IHC is a service used to explore tumour, it can provide additional information not available with standard histological techniques such as H&E. IHC identifies specific molecules within cells that may be involved in the progression of disease and can help determine the origin of neoplasms. IHC can be useful in confirming a diagnosis or providing more precise information about a neoplasm’s origin and type (for example, histiocytic sarcoma that was originally misdiagnosed as meningioma). IHC can also be helpful in identifying the behavior of a tumor and the prognosis for a patient (such as assessing how aggressive a cancer is or whether it has spread to other parts of the body).

IHC service used to explore tumour identify the presence of specific genetic markers. This can be important in determining the risk for certain cancers or other diseases such as Lynch syndrome, an inherited condition linked to colorectal cancer and a greater chance of developing other types of cancer in the uterus, stomach, liver and kidneys.

Western Blotting Service: High-Quality Protein Detection and Analysis

IHC is a powerful tool in the armamentarium of diagnostic surgical pathologists and cancer researchers because it allows them to detect antigens that are only present or up-regulated in diseased tissues. IHC involves using antibodies that bind to specific binding sites on antigens, linking them to enzymes for detection, and then staining the antibody-antigen complex with a colorimetric marker such as horseradish peroxidase. Achieving accurate and reliable IHC results is challenging because of factors such as species and tissue type, fixation duration, quality of fresh or frozen sectioning, antibody characterization and sensitivity, and other technical aspects of IHC.